Antibodies are highly selective agents that can be used to target a variety of cancers and pathogenic infections in humans. Antibody production is usually carried out using mammalian cell culture. However, during production, these cells produce proteases that degrade the antibodies, thus necessitating the use of protease inhibitors. Scientists from the National Institute's of Health […]
Designing a Multiplex Immunoassay: Factors to Consider
Multiplex immunoassays and enzyme-linked immunosorbent assays (ELISA) are used to determine and analyze the presence of an analyte in a sample through the binding of complimentary antigen-antibody pairs. Multiplex immunoassays are useful in cases of limited sample volume or time. molekuul_be | Shutterstock Multiplex immunoassays can be differentiated by the surface to which the antigens […]
ChIP-seq Advantages and Limitations
ChIP-seq, or chromatin immunoprecipitation and sequencing, is a technique that allows researchers to understand transcriptional regulation via mapping of protein-DNA interactions and epigenetic markers on a genome-wide scale. ChIP-seq has several advantages over previous methods, such as ChIP-chip, but like all techniques, ChIP-seq has its limitations. urfin | Shutterstock ChIP-seq ChIP-seq was one of the […]
South African coronavirus variant may ‘obviate’ antibody drugs, former FDA head says
Fox News Flash top headlines for January 6 Fox News Flash top headlines are here. Check out what’s clicking on Foxnews.com. Though COVID-19 vaccines will likely render effective against the South African coronavirus variant – according to an infectious disease expert – the former head of the U.S. Food and Drug Administration (FDA) said the strain may […]
FDA Authorizes Use of Monoclonal Antibody Treatment for COVID-19
MONDAY, Nov. 23, 2020 — A combination of two monoclonal antibodies was granted emergency use authorization (EUA) for the treatment of mild-to-moderate COVID-19, the U.S. Food and Drug Administration announced Saturday. The combination of casirivimab and imdevimab, which must be administered together by intravenous infusion, is approved for use in treating patients ages 12 years […]
Lilly’s antibody IV infusions for coronavirus patients to present ‘unique challenges,’ top officials say
‘Disturbing’ for Cuomo to be ‘shaking confidence’ in coronavirus vaccine: Siegel Fox News Medical contributor Dr. Marc Siegel discusses combatting the coronavirus and reacts to Gov. Cuomo’s remarks on Pfizer vaccine. While Eli Lilly’s investigational monoclonal antibody drug, bamlanivimab, just received FDA emergency approval to treat mild coronavirus patients, top officials voiced concerns over its […]
Lilly's coronavirus antibody treatment gets FDA emergency approval
Lockdowns may actually harm economy, health of country: Dr. Ramin Oskoui Foxhall Cardiology CEO Dr. Ramin Oskoui and oncologist Dr. William Grace discuss Biden coronavirus plans and Pfizer news on ‘The Ingraham Angle.’ The U.S. Food and Drug Administration (FDA) on Monday gave emergency approval to Eli Lilly's investigational monoclonal antibody treatment for coronavirus. The […]
GSK and Vir step up virus antibody treatment trials
British pharmaceutical giant GlaxoSmithKline (GSK) and Californian laboratory Vir Biotechnology on Tuesday announced final stage testing of their potential coronavirus treatment. The phase-three trials will evaluate the effectiveness of their “fully human anti-SARS-CoV-2 monoclonal antibody” VIR-7831 in the early treatment of patients at high risk of hospitalisation. If successful, the companies believe it could increase […]
Regeneron co-founder on the antibody cocktail Trump is taking to fight coronavirus
Regeneron chief scientific officer on the experimental cocktail Trump is taking to fight coronavirus President Trump's physician is treating his coronavirus diagnosis with Regeneron's experimental treatment and his one infusion "seemed to go through very well" and "will last a long time," the company's chief scientific officer explained to "CAVUTO Live" Saturday. White House physician Dr. Sean Conley and other […]
Small study suggests COVID-19 antibody test shows promise
A test that can detect the presence of antibodies to the SARS-CoV-2 virus in the blood of human patients is described in Nature Medicine. This assay, tested in 16 patients, may help to identify individuals whose plasma contains antibodies to SARS-CoV-2, which could potentially be used to treat other patients. Tests that detect the presence […]