UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes — an important step toward understanding the language the body uses to marshal responses to threats. In addition, they discovered that the incorrect use of two of these words can activate the wrong genes, resulting in the […]
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Researchers explore potential role of TARM1 protein in pathogenesis of rheumatoid arthritis
TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and development of collagen-induced arthritis (CIA) was notably […]
Treatment of Graves’ disease
Graves’ disease is a toxic form of hyperthyroidism that may require immediate treatment. Treatment includes antithyroid drugs or medications, radiation therapy with radioactive iodine and surgery. Hyperthyroidism due to Graves’ disease is, in general, easily controlled and safely treated and treatment is almost always successful. However, with most therapies for hyperthyroidism there is an eventual […]