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A new study by researchers in Cleveland Clinic’s Taussig Cancer Institute and Lerner Research Institute describes a novel class of targeted cancer drugs that may prove effective in treating certain common types of leukemia. The results first appeared online in Blood Cancer Discovery. Myeloid leukemias are cancers derived from stem and progenitor cells in the […]
A hormone that helps regulate bone mass is also produced by the heart and could be used to treat people with a dangerous heart rhythm disorder, according to new research we’ve part-funded. Until now, the hormone calcitonin was only thought to be produced by the thyroid gland, with no known effects on the heart. Now, […]
A new International Osteoporosis Foundation (IOF) position paper reviews experimental and clinical evidence showing that hip bone strength estimated by bone mineral density (BMD) and/or finite element analysis (FEA) reflects the actual strength of the proximal femur. The paper “Perspectives on the non-invasive evaluation of femoral strength in the assessment of hip fracture risk,” published […]
Led by researchers at Baylor College of Medicine, a study published in the journal Cell Stem Cell reveals a new mechanism that contributes to adult bone maintenance and repair and opens the possibility of developing therapeutic strategies for improving bone healing. “Adult bone repair relies on the activation of bone stem cells, which still remain […]
(HealthDay)—Obese and overweight older individuals who lose weight have lower bone mineral density (BMD) in their hips, according to a study published in the November issue of Obesity. Daniel E. Kammire, of the Wake Forest University in Winston-Salem, North Carolina, and colleagues gathered data from 77 adults (mean age, 67 years) at baseline, 18 months, […]
For the first time, scientists have been able to study how well synthetic bone grafts stand up to the rigors and ‘strains’ of life, and how quickly they help bone re-grow and repair. Researchers led by Dr. Gianluca Tozzi, at the University of Portsmouth, are the first to examine the strains between bone and graft […]
Why protein is especially in old age, is so important When people get older, this makes it more difficult to Remove. In the age Weight loss in addition to muscle and bone loss, a motor loss and an increased risk of falls. A new study from the US has now shown, however, that a calorie […]
Chordoma is literally a one in a million cancer, with few effective treatment options. A new understanding of the biology behind this tumor type is bringing novel opportunities to light. A partnership pairing scientists from several research centers and a nonprofit organization dedicated to a rare cancer is starting to bear fruit, according to a […]
Children born in the most recent century have bones that reach full maturity earlier—by nearly 10 months in girls and nearly seven months in boys—according to a new study from the University of Missouri School of Medicine. “Our findings show there is a “new normal” for timing when kids’ skeletons will reach full maturity,” said […]
A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to a team of Penn State bioengineers. Their new understanding of the mechanism that allows citrate to aid in bone regeneration will help the researchers develop slow-release, […]