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UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in which survival has plateaued for decades. In the trial, UCSF […]
The latest in a series of laboratory breakthroughs could lead to a more effective way to treat the most common brain cancer in children. Scientists from the University of North Carolina Lineberger Comprehensive Cancer Center, UNC Eshelman School of Pharmacy, and the UNC School of Medicine reported results from early studies that demonstrate how cancer-hunting […]
Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than three years. Many efforts to develop new, targeted treatments have failed over the last […]
New information from the University at Buffalo on how manganese, an essential nutrient, gets into the brain, is helping shed light on a neurological disorder usually associated with industrial overexposure to the metal. In June, Brittany Steimle, a doctoral candidate in biochemistry at UB, received the award for outstanding poster for her presentation on how […]
Hangovers slow your brain down by lowering its electrical activity Hangovers DO slow your brain down by lowering its electrical activity, say scientists who recommend taking a day off and ‘avoiding big decisions’ after a heavy night Study finds alcohol hangovers hampers learning and reward processing in brain University of Victoria analysed 62 subjects – […]
An international team of researchers has uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity, called leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal cells in the hypothalamus. This […]
Researchers have found a surprising new explanation of how young brains are shaped for sexual behavior later in life. Immune cells usually ignored by neuroscientists appear to play an important role in determining whether an animal’s sexual behavior will be more typical of a male or female, according to research led by Kathryn Lenz, an […]
A valuable cache of brain cancer biomedical data has been made freely available to researchers worldwide, say researchers at Georgetown Lombardi Comprehensive Cancer Center. The dataset, REMBRANDT (REpository for Molecular BRAin Neoplasia DaTa) hosted and supported by Georgetown, is one of only two such large collections in the country. Information about the brain cancer data […]
In 1993, neurologist Camilo R. Gomez, MD, coined a phrase that for a quarter century has been a fundamental rule of stroke care: “Time is brain!” “Unquestionably the longer therapy is delayed, the lesser the chance that it will be successful,” Dr. Gomez wrote in an editorial 25 years ago. “Simply stated: time is brain!” […]
Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Where the T-cells go has been unclear, even as immunotherapies are increasingly employed to stimulate the body’s natural ability to fight invasive tumors. Now researchers […]