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Scientists have discovered that the way in which neurons are connected within regions of the brain, can be a better indicator of disease progression and treatment outcomes for people with brain disorders such as epilepsy. Many brain diseases lead to cell death and the removal of connections within the brain. In a new study, published […]
Scientists with UT Southwestern's Peter O'Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication. The findings, published in the Journal of Experimental Medicine, suggest new ways to counteract the weight gain, including a drug recently approved to treat genetic obesity, according to the […]
Patients with clinically diagnosed neurological symptoms associated with COVID-19 are six times more likely to die in the hospital than those without the neurological complications, according to an interim analysis from the Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID). A paper published today in JAMA Network Open presents early results of the global […]
Subarachnoid hemorrhage (SAH)—bleeding from a ruptured aneurysm—leads to delayed cerebral vasospasm (blood vessel constriction) and stroke. SAH morbidity and mortality are high, and therapeutic options are limited. Joyce Cheung-Flynn, Ph.D., and colleagues proposed that SAH downregulates the nitric oxide-protein kinase G (NO-PKG) signaling pathway that normally relaxes cerebral blood vessels. Using a rat model, they […]
People’s ability to perceive speech sounds has been deeply studied, specially during someone’s first year of life, but what happens during the first hours after birth? Are babies born with innate abilities to perceive speech sounds, or do neural encoding processes need to age for some time? Researchers from the Institute of Neurosciences of the […]
Was Pausing Johnson & Johnson’s Covid Vaccine a Good Idea? Paul Gigot interviews Dr. Marty Makary. A Nevada woman who received the Johnson & Johnson COVID-19 vaccine has reportedly undergone three brain surgeries to repair blood clots related to the shot. Emma Burkey, 18, reportedly fell ill about a week after she received the shot […]
A study by the University of Valencia (UV) and the INCLIVA Health Research Institute, of the Clinical Hospital of Valencia, shows that stress during the early stages of life can modify the brain, particularly in women. The study, led by Juan Nácher, Professor of Cell Biology and a member of the INCLIVA Psychiatry and Neurodegenerative […]
NEW YORK (Reuters Health) – In patients with non-small cell lung cancer brain metastases (NSCLCBM) treated with immune-checkpoint inhibitors (ICIs) and upfront steroids, a low neutrophil-to-lymphocyte ratio (NLR) was associated with lower overall survival in a single-center retrospective analysis. “With widespread implementation of ICIs for treatment of NSCLC, many clinicians have concerns that the immunosuppressive […]
A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions. The results, published in Cell Reports, illuminate an important process in the […]
On the surface, Parkinson's disease -; a neurodegenerative disorder -; and melanoma -; a type of skin cancer -; do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease patients are more likely to develop melanoma than the general population. Now, scientists report a molecular link […]