A team led by scientists at Baylor College of Medicine uncovered new evidence supporting a cancer-promoting role for enzyme MAPK6. The study, published in the journal Science Advances, shows that MAPK6 furthers cancer growth by activating the AKT pathway, a known cancer-promoting cellular mechanism. The findings suggest that therapies directed at interfering with MAPK6 activity […]
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New epigenetic editing technique may advance the treatment of many diseases
Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should. By using new CRISPR/Cas9 genome editing technology, in a recent paper in Nature Communications, McGill University researchers have described a new technique that scientists across the world can potentially […]
Experts reveal improved survival for patients with two out of three types of advanced breast cancer
Patients with two out of the three most common types of advanced breast cancer now have an average survival time of at least five years, according to a panel of experts at the Advanced Breast Cancer Sixth International Consensus Conference (ABC 6). When breast cancer spreads to other parts of the body (called metastatic or […]
Spotting colon cancer early with the ‘Google Earth of colonoscopies’
A new optical imaging system in the works could revolutionize the diagnosis of colon cancer. Currently, colonoscopies only manage to detect 39 % of bowel cancer cases in the early stages. Now, the EU-funded PROSCOPE project’s novel screening platform has the potential to save up to half of the 160 000 lives lost in Europe […]
Transgender breast cancer care
The color pink has become ubiquitous with the fight against breast cancer, raising awareness for the most deadly nonskin cancer for females in the United States. Breast Cancer Awareness Month (BCAM) activities are important to encourage screenings and tell the stories of patients who have battled breast cancer, but Annie Brown, MD, said the abundance […]
NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine
The National Institutes of Health has awarded grants to researchers in the Perelman School of Medicine at the University of Pennsylvania to support "highly innovative and broadly impactful" biomedical science through the NIH Common Fund's High-Risk, High-Reward Research program. The seven awards total approximately $8.2 million over five years, The High-Risk, High-Reward Research program catalyzes […]
Skin cancer app fails to identify rare, aggressive cancers
(HealthDay)—A direct-to-consumer machine learning model for detecting skin cancers may not adequately recognize rare, but aggressive, skin cancers, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held virtually from Sept. 29 to Oct 2. Lloyd Steele, M.B.Ch.B., from the University of London, and colleagues assessed the […]
New dashboard intends to drive collaborations in cancer and Covid-19 research
The cancer and Covid-19 research dashboard is a public resource that lists research projects looking at the impact of Covid-19 on cancer care and patients. The dashboard was developed by NCRI, Cancer Research UK, the National Cancer Registration and Analysis Service (NCRAS), and the Cancer Alliance Data, Evaluation and Analysis Service (CADEAS). The intention is […]
Laws designed to aid at-risk women may help catch breast cancer earlier
Laws designed to help women with increased risk for missed breast cancer diagnoses may help catch the disease earlier, according to Penn State College of Medicine researchers. They studied how notification and insurance coverage legislation for women with dense breast tissue affects the stage at which their cancer is diagnosed. More than 40% of women […]
Chemotherapy drug can cause permanent hearing loss in young children with cancer
The chemotherapy drug cisplatin is an effective cancer treatment for many children with cancer, but unfortunately it can cause permanent hearing loss. Results from a new study show that the hearing of very young children is impacted early during treatment and is affected to a greater extent than that of older children. The findings are […]