Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
MALDI Mass Spectrometry in Biomedicine
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
Fluoroscopy Procedure
Fluoroscopy is a diagnostic scan used to study the movement of body structures. This article describes the medical procedure that takes place during a fluoroscopy. X-ray Barium enema showing normal colon mucosa. Image Credit: Richman Photo / Shutterstock What is fluoroscopy? Fluoroscopy shows a continuous X-ray image on a monitor, much like an X-ray movie. […]
Investigating the Molecular Mechanisms of Cancer
Cancer is one of the leading causes of human mortality worldwide. Even though leaps have been made in the fight against it, mortality rates still remain higher than they should be. In recent decades, there has been focused research on the molecular mechanisms of cancer to try and elucidate information that will help improve drug […]
Disparities in lung cancer screening eligibility still exist
(HealthDay)—Despite increases in lung cancer screening eligibility, gender, racial, and ethnic screening disparities may still persist, according to a study published online Jan. 12 in JAMA Network Open. Thomas J. Reese, Pharm.D., Ph.D., from the University of Utah in Salt Lake City, and colleagues used data from the Behavioral Risk Factor Surveillance System (2017 to […]
Study finds racial disparities in breast cancer prognosis testing
Black women have higher recurrence and mortality rates than non-Hispanic white women for certain types of breast cancer, according to a University of Illinois Chicago researcher’s study published recently in JAMA Oncology. Dr. Kent Hoskins, associate professor in the UIC College of Medicine’s division of hematology/oncology, and co-leader of the Breast Cancer Research group in […]
Cancer vaccine helped keep melanoma under control for years in small study
A personalized “cancer vaccine” may help keep a deadly form of skin cancer from growing for years, a small new study in humans suggests. Unlike vaccines that prevent infections, such as measles and influenza, cancer vaccines are a form of immunotherapy that take down cancer cells that already exist. The vaccines train immune cells, called […]
Patients in cancer remission at high risk for severe COVID-19 illness
Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows. Past reports have established an increased risk of severe disease and death for sick or hospitalized cancer patients with COVID-19 compared […]
Study reveals links between fatty liver disease, liver cancer
The United States is facing an epidemic of liver disease linked to obesity. Cases of nonalcoholic fatty liver have more than doubled in the past two decades, now affecting around one quarter of the country’s population. The condition leads to inflammation and scarring in the liver, similar to that caused by alcohol abuse, and increases […]
Researchers identify new gene involved in breast cancer growth
A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment. “The gene ZMYND8 is increased in breast cancer conditions, and higher levels of the gene correlate with poor survival of breast cancer patients,” says Yingfei Wang, Ph.D., […]