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A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation. Although the DNA sequence of the genome is a linear code, like a long sentence, the actual DNA molecule twists and folds in 3-D space, with some sequences […]
A discovery of how stem cells are protected from viruses could inform the development of therapies for use in medicine, research suggests. The finding could help research aimed at boosting the immune response of stem cells—early stage cells with the potential to become specialised tissues—for use in treating disease or damaged tissues. The research identified […]
A study led by St. Jude Children’s Research Hospital has identified a novel risk variant associated with T cell acute lymphoblastic leukemia (T-ALL). The findings appear as an advance online publication in the Journal of the National Cancer Institute. “The inherited genetics underlying this rare type of leukemia were mostly unknown prior to our study,” […]
Small lipid vesicles known as extracellular vesicles are of great interest to cell scientists since it has been discovered that they mediate intercellular communication. Now, Professor Tom Carter’s group has identified a novel pathway for the storage and release of these vesicles from vascular endothelial cells. Working in collaboration with Dr Peter Rosenthal of the […]
Our bodies hold roughly 14 trillion cells, each containing a nucleus with DNA measuring two meters long by 20 atoms wide. To fit inside each nucleus, DNA coils around specialized proteins. These spools of wrapped DNA inhibit gene regulatory proteins from binding to protein-coding stretches along the genome, which help keep genes in the “off” […]
Could a stem cell jab help banish back pain for good? A single jab of stem cells is being tested as a new treatment for lower back pain Doctors say the injection can help re-grow degenerated discs in the spine Researchers hope that trial in Ohio will cure cause of pain instead of symptoms A […]
For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging in the general geriatric population and in HIV-infected people who are responding well to drugs (anti-retrovirals). Even with effective viral control, HIV-infected individuals are at […]
I throw my usuals in the blender: banana, zucchini, spinach, almond milk, nut butter. Then I grab a small sachet of collagen – the latest addition to my pantry – and sprinkle in the powdered contents. Yep, I’m spiking my smoothie with the same stuff that’s been a standard injectable filler in the cosmetic world […]
THURSDAY, Sept. 13, 2018 — Lumoxiti injection has been approved to treat certain instances of relapsed or refractory “hairy cell” leukemia (HCL), the U.S. Food and Drug Administration said Thursday. Lumoxiti (moxetumomab pasudotox-tdfk) is among a novel class of drugs called CD22-directed cytotoxins to treat HCL, the agency said. It was approved for adults who […]
Thirty-five years after an Arizona man cared for his son when he was shot in their native Lebanon, the son is returning that devotion. Both the Rev. John Ibraham Sabbagh and his 54-year-old son, Ebby Sabbagh, are celebrating one year of going strong since the elder Sabbagh received a crucial stem cell transplant. After undergoing […]