A new study provides insights into the cellular mechanisms involved in Christianson syndrome, an X-linked genetic disorder characterized by delayed development, cognitive disability and epileptic seizures as well as difficulties with speech, balance and mobility. This research, published online in the Journal of Neuroscience on Wednesday, Sept. 15, demonstrates how a cellular process known as […]
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Skin cancer growth driven by subset of cellular masterminds
Specialized cells at the leading edge of growing skin cancers dampen immune response and promote cancer invasion, Stanford researchers find. Targeting these cells could lead to effective therapies. An elite population of cancer cells marshal at the leading edges of a growing skin tumor to guide its metastasis and help it evade the body’s immune […]
Cellular origins of pediatric brain tumors identified
A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre (RI-MUHC), and Dr. Michael Taylor, of The Hospital for Sick Children (SickKids), discovered that several types of highly aggressive and, […]
Restricting a key cellular nutrient could slow tumor growth
Remove tumor cells from a living organism and place them in a dish, and they will multiply even faster than before. The mystery of why this is has long stumped cancer researchers, though many have simply focused on the mutations and chains of molecular reactions that could prompt such a disparity. Now, a group of […]