Increased medical spending during the period 1999–2012 generated significant health gains that outweighed the financial costs, according to a National Bureau of Economic Research (NBER) working paper. Researchers led by David M. Cutler, PhD, the Otto Eckstein Chair of Applied Economics, Harvard University, Boston, Massachusetts, measured spending, mortality, and quality of life among elderly Americans. […]
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Survivors Struggle as Scientists Race to Solve COVID Mystery
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. There was no reason to celebrate on Rachel Van Lear’s anniversary. The same day a global pandemic was declared, she developed symptoms of COVID-19. A year later, she’s still waiting for them to disappear. And for experts to come up with […]
Accident Gives MS Doctor Insight Into Patients’ Lives
Editor’s note: The original text has been revised and updated. As Gavin Giovannoni, MBBCh, PhD, an esteemed British multiple sclerosis (MS) expert, set out for his Saturday morning run on Nov. 7, 2020, the world’s weighty problems swirled through his head. Brexit, a U.S. election, a global pandemic, not to mention the daily struggles of […]
Heavy drinking and HIV don’t mix, study finds
Heavy alcohol consumption (three drinks or more/day for women and four drinks or more/day for men) is linked to alterations in immune function among people with HIV. While it has been known that alcohol impacts immune function, it’s been unclear the effect of alcohol on immune function in the context of HIV, a disease whose […]
‘Organs in a dish’ pave the way for personalized medicine in gut and liver disease
One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review in Digestive and Liver Disease, published by Elsevier, scientists highlight some of the established and exciting novel uses for organoids or “organs […]
Protect protruding teeth from damage and long-term consequences
Children with their first or early adult set of teeth that stick out have an increased chance of damaging them, but the risk can be easily reduced without being prohibitively costly. A study undertaken at the University of Adelaide of more than 50,000 children aged under 19 years published in the journal Dental Traumatology, confirms […]
Large multi-ethnic genome-wide association study of asthma identifies novel associations
A large, multi-ethnic genome-wide association study (GWAS) of asthma identified novel associations with potential relevance for asthma susceptibility in older adults of diverse racial backgrounds. The study, “Large-scale, multi-ethnic genome wide association study identifies novel loci contributing to asthma susceptibility in adults,” appears in the April issue of the Journal of Allergy and Clinical Immunology. […]
Removal of ‘zombie cells’ alleviates causes of diabetes in obese mice
Mayo Clinic researchers and their collaborators have shown that when senescent cells — also known as “zombie cells” — are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear. The findings appear in Aging Cell. Inflammation and dysfunction of fat tissue cause some […]
Another possible consequence of the opioid epidemic: hormone deficiencies
Many people who use opioid medications long term do not produce enough testosterone or another important hormone, cortisol, according to a new study. Results of what the researchers called “the most up-to-date and most comprehensive clinical review of endocrine effects of long-term opioid use” are being presented Sunday at ENDO 2019, the Endocrine Society’s annual […]
Sniffing out Parkinson’s disease
Parkinson’s disease is a neurodegenerative disorder that leads to progressive brain cell death and extensive loss of motor function. Despite much research being conducted on this disease, there are no definitive diagnostic tests currently available. Now, researchers report the identification of compounds that make up the signature odor of the disease with the help an […]