Patients with a greater than 10 pack/year history of smoking tend to develop an especially dangerous form of head and neck squamous cell cancer (HNSCC) for which prognosis remains poor and treatments have changed little during the past two decades. However, recent phase 1 clinical trial results by the Head and Neck Cancer Group at […]
Evidence of clinical inertia in management of T2DM
(HealthDay)—Many patients with type 2 diabetes (T2D) who have a hemoglobin A1c (HbA1c) level expected to trigger treatment intensification often have treatment inappropriately delayed, according to a research letter published in the July issue of Diabetes Care. Kevin M. Pantalone, D.O., from the Cleveland Clinic, and colleagues identified a cohort of 7,389 patients with T2D […]
Health Sciences South Carolina lights up a FHIR-based clinical data repository
While the FHIR specification continues gaining momentum, early success stories are happening among hospitals around the country. Health Sciences South Carolina, for instance, built a FHIR-based clinical data repository infrastructure to create an inter-institutional culture of collaboration for learning from clinical practice, and empowering action through access to data while advancing evidence. "Our goal was […]
Cell ‘chatter’ discovery could open clinical trial opportunity for fatal childhood brain tumour
Brain tumours are hard to treat. But even this is a harrowing understatement for some forms of the disease. Diffuse intrinsic pontine glioma (DIPG) is one such example. These rare brain tumours almost exclusively affect children, and they’re invariably fatal. “Almost all children with DIPG sadly die within a couple of years of diagnosis,” says […]