Escherichia coli bacteria are constitutive members of the human gut microbiota. However, some strains produce a genotoxin called colibactin, which is implicated in the development of colorectal cancer. While it has been shown that colibactin leaves very specific changes in the DNA of host cells that can be detected in colorectal cancer cells, such cancers […]
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Conserved networks of collateral susceptibility to antibiotics in Escherichia coli
LSTM’s Dr. Adam Roberts is a co-author on a new paper published in Nature Communications which reports conserved collateral susceptibility to antibiotics in the human pathogen Escherichia coli. Collateral susceptibility is the phenomenon whereby the development or acquisition of resistance to one antibiotic changes the susceptibility of that bacteria to another antibiotic, sometimes of a […]