Health News

Potential new therapies for Alzheimer’s are revealed through network modeling of its complex molecular interactions

Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease (LOAD), as well as a promising therapeutic candidate for treatment, according to a study in the journal Neuron. LOAD is the most prevalent form of dementia among people over age 65, a […]

Health News

Silencing gene expression to cure complex diseases

Many people think of new medicines as bullets, and in the pharmaceutical industry, frequently used terms like “targets” and “hits” reinforce that idea. Immuneering co-founder and CEO Ben Zeskind ’03, Ph.D. ’06 prefers a different analogy. His company, which specializes in bioinformatics and computational biology, sees many effective drugs more like noise-canceling headphones. Rather than […]

Health Problems

Tetris gameplay reveals complex cognitive skills

In a fraction of a second, a colorful digital block shaped like the letter “L” falls from the top of the computer screen. In even less time, fingers float across a controller, striking the arrow keys in rapid succession to rotate the figure so it falls in line with a computerized stack of shapes. Form […]

Health Problems

Kidney patients are the most complex patients

A study published in JAMA Network Open shows nephrologists treat the most complex patients. As ERA-EDTA president Professor Carmine Zoccali explains, kidney patients are highly vulnerable and need special care, but nephrology is a neglected discipline in many European healthcare systems. According to the ERA-EDTA, it is time for better financial funding of nephrology as […]

Health Problems

Theranostic complex with two toxic modules shows high toxicity for tumour cells

Emerging cancer nanotechnology enables targeted delivery of drug payloads to cancer sites with concomitant reduction of side effects due to reduced accumulation in critical organs. This prompts research into nanocarriers of therapeutic cargo and contrast agents, allowing combined cancer therapy and tumour visualization, respectively. Researchers from Lobachevsky University of Nizhny Novgorod, Russia, have implemented such […]

Health News

ACA expansion did not improve access to complex surgeries for low-income/minority patients

A first look at the Affordable Care Act (ACA)’s Medicaid expansion finds that despite expectations, there was no increased use of complex surgical procedures at high volume hospitals—a proxy for high quality hospitals—among ethnic/racial minorities and low-income populations. The findings came from comparing surgery records from high-volume hospitals in three states that opted in to […]

Health Problems

Synthetic DNA technology provides a novel strategy for effective delivery of a complex anti-HIV agent

Scientists at The Wistar Institute have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics for infectious agents as well as for diverse implications in therapeutic delivery. This critical development was published online in the journal […]

Health Problems

Physicians with medicine/psych training can help complex cases

(HealthDay)—Physicians boarded in both medicine and psychiatry can offer a way to address some of the challenges associated with caring for medical patients with psychiatric comorbidities, according to an article published in Psychiatric Times. Noting that patients with psychiatric issues frequently receive substandard medical care in the hospital setting, the article discusses combined training for […]