Memories are part of our lives, the good and the bad. Through our senses, experiences reach our brain where networks of nerve cells encode them into a memory. It was previously unclear why only certain nerve cells join together for this purpose. Researchers from the Max Planck Institute of Psychiatry in Munich have now discovered […]
Home »
A tailor-made molecule that ties nerve connections
Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms of certain neurological injuries and diseases, while on the microscopic level it was able to establish and repair connections between neurons. This proof-of-principle study […]
Alterations in hippocampal structural connections differentiate responders of electroconvulsive therapy
A new study in people with major depression reports that electroconvulsive therapy (ECT) induces changes in the fibers connecting the hippocampus to brain regions involved in mood and emotion. Only patients who responded to the treatment showed these changes, and those who had the greatest changes in hippocampal pathways also showed the largest improvements in […]
Immune cells destroy healthy brain connections, diminish cognitive function in obese mice
Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice published in JNeurosci. The research suggests that microglia may be a potential therapeutic target for one of the lesser known effects of this global health epidemic on the brain. Nearly two […]
Unconventional connections: How inhibition hones cortical selectivity
Our brains do a remarkable job of encoding visual information about the world around us, providing an almost instantaneous report about rapidly changing conditions that is critical for guiding our behavior. Integral to the brain’s encoding mechanism is the presence of neurons that respond selectively to specific visual features, generating electrical activity that reliably signals […]