Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases. Much less genetic engineering has been devoted to Culex genus mosquitoes, which spread devastating […]
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COVID-19: Men create more antibodies after asymptomatic infections and keep them longer
As COVID-19 has swept across the globe, it seems that high transmission rates have partly been driven by a large number of people catching the virus, not experiencing symptoms and then unknowingly passing it on. Despite this, the screening of asymptomatic people for signs of infection hasn’t been widespread, due to costs and limits on […]
Researchers create artificial lung to support pre-term babies in distress
An international team led by current and former McMaster University researchers has developed an artificial lung to support pre-term and other newborn babies in respiratory distress. The group has proven the concept using a live piglet, a major step along the route toward approval for use in humans, where the portable device could save many […]
Physicians create guide for identifying, treating vaping lung illness
As lung injuries from vaping continue to rise across the United States, Rochester physicians and New York health leaders developed a new tool to assist in the diagnosis and treatment of e-cigarette, or vaping, product use associated lung injury (EVALI). The diagnostic/treatment algorithm, published in The Lancet Respiratory Medicine, complements and expands upon early guidance […]
Scientists create brain-mimicking environment to grow 3-D tissue models of brain tumors
A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response. The study was published today in Nature Communications. The researchers created models that include brain-derived extracellular matrix (ECM) […]
Researchers create organoid of a brain region to study cognitive disorders
In a lab dish, Yale researchers modeled two brain structures and their interactions to shed light on the origins of neuropsychiatric diseases. In-Hyun Park, associate professor of genetics, and his team created an organoid of the thalamus, a major hub that integrates sensory information and relays it to different areas of the brain. Organoids are […]
How to create health care centaurs—half doctors and half managers
If hospital doctors around the world often struggle to become the half-professionals and half-managers that modern healthcare organizations need, the main responsibility is not their resistance to change, but the lack of effective support from the organization, according to a study by Marco Sartirana (CERGAS, Bocconi University), Graeme Currie (Warwick Business School), and Mirko Noordegraaf […]
New York girl, 12, has ankle reattached backward to create new knee after bone cancer diagnosis
Delaney Unger, who is now cancer-free for over a year, attaches a prosthesis to her ankle, which now acts as her knee joint for maximum flexibility. (Fox 5 NY. ) A 12-year-old who was diagnosed with bone cancer two years ago has been able keep up with her love of dancing after doctors created a […]