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Patients with a unique cellular disorder are helping researchers understand a series of health complications better. For the first time, researchers led by Newcastle University, UK have identified a group of patients with neurological disease who lack a critical cell process called autophagy. The work is published today in the New England Journal of Medicine. […]
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumour immune response. The preclinical research, published today in Nature Immunology, suggests that […]
In a new research letter published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine, researchers examine whether preprint data on the use of the corticosteroid dexamethasone influenced clinical practice in treating COVID-19 critical care patients throughout Australia. Preprints are scientific papers that are posted online rapidly, before peer review. […]
Despite a 30% drop in global maternal deaths from 1990 to 2015, 280,000 women still die annually due to complications of pregnancy and childbirth. Sixty-six percent of these deaths occur in sub-Saharan Africa. It is well established that timely access to critical maternal health services can reduce deaths of pregnant women by 15-50%. However, travel […]
More than one-third of working Americans don’t get enough sleep, and the problem is greatest among the police, the military, health care workers and truckers, researchers report. Their analysis of data from more than 150,000 employed adults between 2010 and 2018 also found that the rate of inadequate sleep (7 hours or less) rose from […]
A protein that is critical in controlling replication of West Nile and Zika viruses—and could be important for developing therapies to prevent and treat those viruses—has been identified by a Georgia State University biologist and his research group. The researchers found Z-DNA binding protein 1 (ZBP1) is a sensor that plays a significant role in […]
Deadly ‘zombie’ deer disease could spread to humans A deadly ‘zombie’ deer disease could possibly spread to humans, experts are warning. Republican Rep. Ralph Abraham isn't going to wait for the deadly, so-called “zombie” deer disease to spread to his home state of Louisiana before taking action. Abraham, who represents the state’s 5th congressional district, […]
In experiments using mice, a team of UC San Francisco researchers has discovered a gene that plays an essential role in noise-induced deafness. Remarkably, by administering an experimental chemical—identified in a separate UCSF lab in 2013—that acts on the pathway linking this gene to hearing loss, they found that they could prevent noise-induced deafness in […]