The cover for issue 55 of Oncotarget features Figure 3, “Romidepsin exhibits anti-tumor effect in xenograft model of DDLPS,” by Seligson, et al. Here the researchers present in silico, in vitro, and mouse xenograft studies that suggest that specifically targeting HDAC2 reduces MDM2 expression and has anti-tumor affects in DDLPS. In a murine DDLPS xenograft […]