Researchers who explore children’s lives need to carefully design the research to ensure the children can articulate their opinions and experiences in a meaningful way. Participatory child research actively engages children throughout the research process—as opposed to children serving only as the subject being studied—and it requires the right approach and methodology. One of the […]
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New antibody rationally designed for better tumor inhibition
Recently, Prof. Xie Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. Yan Xiyun’s lab from the Institute of Biophysics, reported the structural basis of mAb AA98’s inhibition on CD146-mediated endothelial cells (EC) activation and designed higher affinity monoclonal antibody HA98 for cancer treatment. […]
Big data powers design of ‘smart’ cell therapies for cancer
Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research. In two new papers, scientists at UC San Francisco and Princeton University present complementary strategies to crack this problem with “smart” cell therapies—living medicines that remain inert unless triggered by combinations of proteins that only ever […]
Design thinking can change the treatment of young people with psychological problems
Behavioural scientists are increasingly designing games that can be used preventatively or as therapy for young people with emerging or chronic psychological problems, such as anxiety or depression. Nevertheless, the development and validation of these games is still in its infancy. According to behavioural scientists Hanneke Scholten and Isabela Granic of Radboud University, a form […]
Small changes to cafeteria design can get kids to eat healthier, new assessment tool finds
While a growing body of research suggests that small changes to a school environment can help reduce childhood obesity and improve nutrition, 80 percent of school-aged children still fall short of national dietary guidelines for fruit and vegetable intake. New research from the University of Notre Dame suggests ways to approach this problem in elementary […]