Your baby delights you but he’s causing you concern. Why is it so hard to get him to look at you? Why doesn’t he gesture as much as other babies you know? Your relatives say you worry too much. They blame your parenting for the child’s frequent tantrums. Still, you wonder: “Could my baby have […]
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Discovery in cell development changes understanding of how genes shape early embryos
Our bodies hold roughly 14 trillion cells, each containing a nucleus with DNA measuring two meters long by 20 atoms wide. To fit inside each nucleus, DNA coils around specialized proteins. These spools of wrapped DNA inhibit gene regulatory proteins from binding to protein-coding stretches along the genome, which help keep genes in the “off” […]
Shortcut strategy for screening compounds with clinical potentials for drug development
Developing a new drug often takes years and costs hundreds of millions of dollars. A shortcut has now been reported in a study led by City University of Hong Kong (CityU), which can potentially reduce the time and costs of developing new drugs by sorting out the high potential candidates from a long list of […]
Pediatric Anesthesia Does Not Affect Development Outcomes
MONDAY, Nov. 5, 2018 — Young children who have surgical procedures that require general anesthesia do not have an increased risk for adverse child development outcomes, according to a study published online Nov. 5 in JAMA Pediatrics. James D. O’Leary, M.D., from The Hospital for Sick Children in Toronto, and colleagues examined the correlation between […]
Engrafted stem cell-derived lung organoids that model human lung development
Researchers have now grown lung organoids from human embryonic stem cells (hESCs) that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs. The strategy is the first to generate both lung distal progenitor cells and mature AT1-like cells. The study is published in […]
Better statistical methods to understand gene interactions leading to cancer development
Research led by Hui-Yi Lin, Ph.D., Associate Professor of Biostatistics at LSU Health New Orleans School of Public Health, has developed another novel statistical method for evaluating gene-to-gene interactions associated with cancer and other complex diseases. The Additive-Additive 9 Interaction (AA9int) method is described in a paper published in Bioinformatics. “This method can identify combinations […]
Estrogen could promote healthy development of preterm infants
Premature birth alters the balance of interneurons in the cerebral cortex that can be restored with estrogen treatment, according to a study of human brain tissue and preterm rabbits published in JNeurosci. Infants born prior to a full-term pregnancy are at increased risk of neurobehavioral disorders linked to defects in interneurons, which continue to develop […]
New research underscores the importance of language development in low-income, high-risk children
Language sets the stage for how children grow, develop, and learn. University of Miami Assistant Professor of Psychology Lynn Perry, whose research focuses on language and cognitive development in children, says a child’s early years of language development are critical for the fundamentals of school readiness, such as literacy skills and social and emotional growth. […]