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Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. An enzyme called ABCE1 is responsible for this process and turns out to be remarkably plastic as Ludwig-Maximilians-Universitaet (LMU) in Munich biophysicists report. Ribosomes translate the genetic information, which is first transcribed into messenger RNAs by polymerases, into the […]
Scientists from Nanyang Technological University, Singapore (NTU Singapore) have pinpointed how a special class of plant-derived enzymes, known as peptide ligases, work to join proteins together. Such binding is an important process in the development of drugs, for example in specifically attaching a chemotherapy drug to an antibody that recognises tumour markers to target cancer […]
The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University. The newly discovered mechanism reveals the molecular link between the enzyme’s daily fluctuations and its energy-regulating role in the body, according to a study […]
In past years, the demand for cobalt has been on the increase due to its many applications. For one thing, the metal is a crucial component of rechargeable lithium-ion batteries for smartphones and electric cars. Around 60% of the world’s cobalt supply comes from the mineral-rich Katanga Copper belt, in the Democratic Republic of the […]
A groundbreaking discovery by chemists at The University of Texas at San Antonio (UTSA) will have a significant impact on how pharmaceutical companies develop new drug treatments. The breakthrough involves fluorine, which forms the second strongest carbon bond (C-F) known to science, after the carbon-silicon (C-S) bond. Fluorine is one of the most fundamental elements […]
Over-the-counter (OTC) drugs and dietary supplements are widely used and popular, with US households spending an average of almost USD 350 annually on OTC products. In 2006 an average of EUR 67.50 was spent per person on OTC products in Germany. The use of various OTC drugs and dietary supplements is highly prevalent in Europe […]