TUESDAY, Oct. 27, 2020 — School-aged children seem to have the least severe disease for different infectious diseases, according to a study published online Oct. 15 in Scientific Data. Judith R. Glynn, Ph.D., from the London School of Hygiene & Tropical Medicine, and Paul A.H. Moss, M.D., Ph.D., from the University of Birmingham, both in […]
Vaping epidemic puts adolescents at risk for potentially fatal lung disease
Adolescent use of e-cigarettes and vaping products is at epidemic proportions, yet the adverse health effects are understudied, with almost no data on younger patients. The problem is sizable as children start vaping at a younger and younger age. Recent estimates show that 9.6 percent of eighth graders vape nicotine or THC (tetrahydrocannabinol, the main […]
‘Patient activation’ may improve quality of life in individuals with kidney disease
Researchers previously demonstrated that online peer mentoring for individuals with chronic kidney disease (CKD) improves patient activation—or patients’ willingness and ability to take actions to manage their health and care—and quality of life (QOL). Now the investigators have looked at the correlation between QOL and patient activation among patients with CKD who participated in an […]
Researchers develop a simplified method to modify disease signaling with light
Most diseases are caused by aberrant cell signaling processes, and basic research in cell signaling is needed to identify targets for future therapeutic approaches, especially in cases where no cures or effective treatments are currently available. Cellular optogenetics uses light to precisely control cell signaling in space and over time, making it an invaluable technique […]
Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery. This month, a team of scientists and clinicians led by the University of Toronto’s Faculty of Dentistry say they’ve found the reason why—and […]
Social isolation increases anxiety and asymmetry in brain atrophy in Alzheimer’s disease
Researchers at the Universitat Autònoma de Barcelona (UAB) have conducted a study which allows estimating the effects of isolation in the current pandemic scenarios in elderly patients with dementia. The findings could serve as a guide to the rethinking of these conditions after the COVID-19 crisis. The study was published in a special edition of […]
How night vision is maintained during retinal degenerative disease
New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal. The study in mice suggests that second-order neurons in the retina, which relay visual signals to the retinal ganglion cells that project into the brain, […]
Shared protein fingerprint could simplify treatment of common inherited heart disease
Hypertrophic cardiomyopathy is the most common inherited heart disease, marked by an abnormally thickened heart muscle that can obstruct blood flow and lead to sudden death in young adults. A dizzying array of over 1,400 genetic mutations can lead to the disease, puzzling doctors on how to treat so many unique varieties. But in new […]
Biologic therapy for psoriasis may reduce heart disease
Patients with psoriasis treated with biologic therapy, which are protein-based infusions to suppress inflammation, had a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research published today in Circulation: Cardiovascular Imaging, an American Heart Association journal. Chronic inflammation in people with psoriasis is associated with a higher risk of developing […]
Host tissue T cells may have an unexpected role in graft-versus-host disease
Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor’s healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can be life-saving, a major complication is the development of graft-versus-host disease (GVHD), which causes significant morbidity and can be fatal. Before allogenic […]