As medicine becomes both bigger and more personalized, the need for massive databases of patient records, such as the 1 million person All of Us Research Program, become increasingly essential to fueling both new discoveries and translational treatments. But the looming, lingering question is to what degree are individual patients willing to share medical records […]
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Discharge incentives in emergency rooms could lead to higher patient readmission rates
In an effort to address emergency department overcrowding, pay-for-performance (P4P) incentive programs have been implemented in various regions around the world, including hospitals in Metro Vancouver. But a new study from the UBC Sauder School of Business shows that while such programs can reduce barriers to access for admitted patients, they can also lead to […]
Evaluating blood flow is key to early diagnosis and treatment for people with critical limb ischemia
Non-invasive techniques and devices for assessing blood flow and other diagnostic considerations for people with critical limb ischemia are addressed in a new scientific statement from the American Heart Association, published in the Association’s flagship journal Circulation. The statement provides perspective on the strengths and limitations of current imaging techniques, including the ankle-brachial index, toe […]
New synthesis method opens up possibilities for organic electronics
Semiconducting polymers, very large chain-like molecules made from repeating sub-units, are increasingly drawing the attention of researchers because of their potential applications in organic electronic devices. Like most semiconducting materials, semiconducting polymers can be classified as p-type or n-type according to their conducting properties. Although p-type semiconducting polymers have seen dramatic improvements thanks to recent […]
New material could make it easier to remove colon polyps: Gel cushion used to elevate polyps during endoscopy could reduce the risk of tearing the colon lining
More than 15 million colonoscopies are performed in the United States every year, and in at least 20 percent of those, gastroenterologists end up removing precancerous growths from the colon. Eliminating these early-stage lesions, known as polyps, is the best way to prevent colon cancer from developing. To reduce the risk of tearing the colon […]
Molecular biophysics: The ABC of ribosome recycling
Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. An enzyme called ABCE1 is responsible for this process and turns out to be remarkably plastic as Ludwig-Maximilians-Universitaet (LMU) in Munich biophysicists report. Ribosomes translate the genetic information, which is first transcribed into messenger RNAs by polymerases, into the […]
Widespread aspirin use despite few benefits, high risks
Medical consensus once supported daily use of low dose aspirin to prevent heart attack and stroke in people at increased risk for cardiovascular disease (CVD). But in 2018, three major clinical trials cast doubt on that conventional wisdom, finding few benefits and consistent bleeding risks associated with daily aspirin use. Taken together, the findings led […]
Multiple injection safety violations found in New Jersey septic arthritis outbreak: Tainted knee injections infected 41 patients, caused $5 million in Medicare claims
Multiple violations of injection safety and infection prevention practices — from lack of handwashing to inappropriate re-use of medication vials — were identified after an outbreak of septic arthritis at a New Jersey outpatient facility in 2017, according to an investigation published today in Infection Control & Hospital Epidemiology, the journal for the Society for […]
A single measurement may help determine kneecap instability risk
Knee injuries can be a scourge to collegiate and pro athletes alike, but Penn State researchers say a single measurement taken by a clinician may help predict whether a person is at risk for knee instability. The researchers found that measuring the distance between the tibial tubercle (TT) — a bony bump on the tibia, […]
Larger drug trials that intervene earlier needed for Alzheimer’s disease
There are currently no drugs that stop or inhibit Alzheimer’s disease. Despite drug trials showing plaque reduction in the brain, the patients’ cognitive function did not improve. Would the results be different if it were possible to design studies that intervene much earlier on in the disease, before cognition is affected? This is what an […]