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Medical consensus once supported daily use of low dose aspirin to prevent heart attack and stroke in people at increased risk for cardiovascular disease (CVD). But in 2018, three major clinical trials cast doubt on that conventional wisdom, finding few benefits and consistent bleeding risks associated with daily aspirin use. Taken together, the findings led […]
Better care and more research into treatments for people experiencing a first manic episode are urgently needed, according to researchers at the NIHR Maudsley Biomedical Research Centre. The study, published today in The Lancet Psychiatry by a team of international experts, describes patchy and inconsistent care, widespread failure to detect bipolar disorder early enough, and […]
For the estimated 100 million U.S. adults and children living with nonalcoholic fatty liver disease (NAFLD), whether or not they have liver cirrhosis, or scarring, is an important predictor for survival. Yet it’s difficult and invasive to detect liver cirrhosis before it is well advanced. In an effort to quickly and easily identify people at […]
Parkinson’s disease is a neurodegenerative disorder that leads to progressive brain cell death and extensive loss of motor function. Despite much research being conducted on this disease, there are no definitive diagnostic tests currently available. Now, researchers report the identification of compounds that make up the signature odor of the disease with the help an […]
Combining medications that suppress the immune system has been successful in treating young patients with Crohn’s disease, but some physicians have been reluctant to use this strategy in older patients because of concerns about safety. Now an Alimentary Pharmacology & Therapeutics study indicates that older patients can be safely and effectively treated with such combined […]
New research shows us just how important primary care physicians are in prolonging our lives. Every 10 additional primary care physicians per 100,000 people in the United States was associated with a 51.5-day increase in life expectancy during the decade from 2005 to 2015, according to a study led by researchers at the Stanford University […]
Migraine with aura was associated with an increased risk of ischemic stroke in the Atherosclerosis Risk in Communities study, but a recent post-hoc analysis published in Headache reveals unexpected results suggesting that onset of such migraines before age 50 years is not associated with such risk. Later onset of migraine with aura was linked with […]
Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified gene recombination in neurons that produces thousands of new gene variants within Alzheimer’s disease brains. The study, published today in Nature, reveals for the first time how the Alzheimer’s-linked gene, APP, is recombined by using the same type of enzyme found in HIV. Using […]
Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain’s complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette of protein tools. A multidisciplinary team of 14 researchers from the Howard Hughes Medical Institute’s Janelia Research Campus and other institutions […]
A simple test taken within a week of a stroke may help predict how well people will have recovered up to three years later, according to a study published in the October 17, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. “We found that this test, which takes less […]