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A shadow over the promising inhaled interferon beta COVID-19 therapy has been cleared with the discovery that although it appears to increase levels of ACE2 protein—coronavirus’ key entry point into nose and lung cells—it predominantly increases levels of a short version of that protein, which the virus cannot bind to. The virus that causes COVID-19, […]
People with chronic obstructive pulmonary disease (COPD) and people who currently smoke may have higher levels of a molecule, called angiotensin converting enzyme II (ACE-2), in their lungs according to a study published in the European Respiratory Journal today. Previous research shows that ACE-2, which sits on the surface of lung cells, is the ‘entry […]
THURSDAY, Dec. 27, 2018 — Universal vaccination against Neisseria meningitidis serogroup B (MenB) at college entry does not appear to be cost-effective, according to a study published online Dec. 17 in the American Journal of Preventive Medicine. Ira L. Leeds, M.D., from Johns Hopkins University in Baltimore, and colleagues estimated the costs and benefits of […]
Stress demands the heart to work harder and faster. To keep pace, the muscle must make its fuel at an accelerated rate. Bursts of calcium entering mitochondria—the cell’s powerhouses—normally help control energy output, but too much calcium can overload the system and lead to cell death. Now research led by Jefferson (Philadelphia University + Thomas […]