More than 15 million colonoscopies are performed in the United States every year, and in at least 20 percent of those, gastroenterologists end up removing precancerous growths from the colon. Eliminating these early-stage lesions, known as polyps, is the best way to prevent colon cancer from developing. To reduce the risk of tearing the colon […]
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Scientists discover origin of cell mask that hides stomach cancer
A layer of cells that look like normal stomach lining on top of sites of stomach cancer can make it difficult to spot after removal of a Helicobacter pylori infection. In a recent study, researchers from Hiroshima University have uncovered the origin of this layer of cells: it is produced by the cancer tissue itself. […]
‘Organs in a dish’ pave the way for personalized medicine in gut and liver disease
One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review in Digestive and Liver Disease, published by Elsevier, scientists highlight some of the established and exciting novel uses for organoids or “organs […]
New way to protect against high-dose radiation damage discovered
Radiotherapy, a common treatment for cancer, is one of the most effective ways to destroy cancer cells and shrink tumours. Around 50% of patients with tumours located in the gastrointestinal cavity (liver, pancreas, colon, prostate, etc) receive this type of treatment, which has increased cancer survival rates over the past decades. However, intensive radiation therapy […]
When mucus can be key to treating colon and airway diseases
New research reveals how healthy cells in our bodies produce mucins — the main component of mucous, which protects our intestine and airway from pathogens, toxins and allergens. Scientists have already linked defects in mucins secretion to airway and colonic diseases, such as asthma or ulcerative colitis. Now, researchers at Malhotra’s laboratory in Barcelona, reveal […]
Researchers wake-up DNA from soil bacteria to discover novel acid antibiotic
Scleric Acid has been discovered by capturing and engineering a DNA fragment from soil bacteria Streptomyces sclerotialus, and could help fight bacterial infections — by researchers at the School of Life Sciences and Department of Chemistry, University of Warwick. A team led by Dr Christophe Corre and Dr Manuela Tosin have had published in Chemical […]
Increased mortality in children with inflammatory bowel disease
Children who develop inflammatory bowel disease (ulcerative colitis or Crohn’s disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports. It is therefore important that patients who are diagnosed as children are carefully monitored, argue the researchers behind […]
Doctors issue caution over missed cancer diagnoses tied to immune disorder: Study shows HLH diagnosis may obscure underlying malignancies
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs — often causing death — doctors frequently […]
First gut bacteria may have lasting effect on ability to fight chronic diseases: Discovery could eventually allow doctors to establish beneficial gut bacteria in infants right after birth
New research showing that the first bacteria introduced into the gut have a lasting impact may one day allow science to adjust microbiomes — the one-of-a-kind microbial communities that live in our gastrointestinal tracts — to help ward off serious chronic diseases. Findings by U of A microbial ecologist Jens Walter and his colleagues suggest […]
A pill for delivering biomedical micromotors
Using tiny micromotors to diagnose and treat disease in the human body could soon be a reality. But keeping these devices intact as they travel through the body remains a hurdle. Now in a study appearing in ACS Nano, scientists report that they have found a way to encapsulate micromotors into pills. The pill’s coating […]