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The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19. Some COVID-19 patients experience an immune response in which the immune system unleashes excessive amounts of proteins that trigger inflammation—called a “cytokine storm”—that can lead to […]
Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body’s natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy. The findings, published today in the journal Science Translational Medicine, open […]
2020 presidential candidates trade insults on coronavirus pandemic response Fox News medical contributor Dr. Nicole Saphier and owners of Steepologie Teas Andrea Raetzer and Joe Raetzer discuss which candidate delivered the message Americans wanted to hear. Biotech company Moderna announced on Tuesday that its coronavirus vaccine candidate elicited immune responses in older adults from a […]
Researchers have created a mathematical model that can determine the impact of the immune system on tumor evolution. The information gained from using this model may be able to be used to predict whether immunotherapy is likely to be effective for a patient’s cancer, helping to guide treatment decisions. Immune cells recognize tumors by detecting […]
Melbourne researchers have discovered that killer T cells, key immune cells in fighting viral infections, are present at much lower levels in people with COVID-19, compared to influenza or glandular fever. Publishing their findings today in PNAS, the team from the Peter Doherty Institute for Infection and Immunity (Doherty Institute) looked at 22 COVID-19 samples […]
A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency (SCID). The results of this work was presented Tuesday in the medical journal Blood Advances published by the American Society of Hematology. Routine neonatal screening, although not yet available in Quebec, has led to an increase […]
Anyone who spends time surfing the net knows it is commonplace to see online advertisements making dubious health claims. Now, with the arrival of COVID-19, misinformation related to the pandemic has proliferated. Dr. Christen Rachul, director of research at the Office of Educational & Faculty Development and assistant professor in the Rady Faculty of Health […]
The team from the University of Nottingham’s Schools of Pharmacy and Life Sciences have found that the surface shape (topography) and chemical composition of polymer materials can be changed to create materials that control the body’s immune response. This could have future applications in the fight against rejection of medical devices including artificial joints, dental […]
A new study by members of the Cumming School of Medicine (CSM) at the University of Calgary finds niacin, commonly called vitamin B3, combined with chemotherapy can help immune cells attack glioblastoma (a type of brain tumor), dramatically slowing progression of the disease, in mice. The results published in Science Translational Medicine found the lifespan […]
The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival. For microscopical analysis, full tissue samples provide a better picture of the immune cell activity in the tumor compared to tissue-sparing punch biopsies. A team led by the visceral surgeon Elisabeth S. Gruber and […]