Health News

Transporter imbalance implicated in schizophrenia

Alterations in the balance of two chloride ion transporters may be responsible for cognitive deficits in schizophrenia, according to a Northwestern Medicine study published in Science Advances. These alterations cause the most important inhibitory current in the brain, called GABAA, to become excitatory. Inhibiting the transporter activity with bumetanide, an FDA-approved diuretic, rescued cognitive symptoms […]