Health News

Transporter’s role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction and chronic infections. To explore the cellular and molecular mechanisms underlying the role of NKCC1 in the intestinal pathology, Eric Delpire, Ph.D., and […]

Health News

Acid reflux drugs linked to increased fracture risk in kids

Proton pump inhibitors—a widely used class of drugs used to treat acid reflux and related symptoms—may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology and Nutrition (JPGN). “This study suggests an increased risk of fracture among otherwise healthy pediatric patients exposed to PPIs,” […]

Health News

Certain factors linked with discontinuing breast cancer therapy

For women with hormone receptor-positive breast cancer, long-term endocrine therapy can greatly reduce the risk of recurrence. Many women, especially those in underserved populations, do not continue treatment, however. A new Psycho-Oncology study uncovers some of the factors that may be involved. In the study of 1,231 women who completed questionnaires, 59% reported at least […]