The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids. A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and the Vrije Universiteit Brussel (VUB), in Belgium, describes a number of […]
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Lung cancer drug could be repurposed to target ‘zombie’ proteins linked to leukemia
A new study by scientists at the University of Liverpool highlights how a clinically-approved lung cancer drug could potentially be ‘repurposed’ to design new treatments for future cancer therapies. The research, published in Science Signaling, focuses on a protein called TRIB2, which is linked to promoting survival and drug resistance in solid tumours and blood […]
Four Girls Reunite After They Beat Cancer Together at the Same Hospital: 'It's Amazing to See'
Three years ago, McKinley, Chloe, Ava and Lauren were all in treatment for cancer at a Florida hospital. The quartet relied on each other to get through the arduous process, and on Monday they reunited for a photo shoot as cancer survivors. The girls, all between the ages of 4 and 5, take a photo […]
Nanoparticle therapeutic restores function of tumor suppressor in prostate cancer
Think of it as a cancer therapy zag instead of a zig. While many groups are developing cancer therapies to target proteins and pathways that are highly active in cancer cells, a team of investigators from Brigham and Women’s Hospital and Boston Children’s Hospital, with collaborators at Memorial Sloan Kettering Cancer Center, is taking a […]
Novel role of protein in important pathways that lead to cancer malignancy
Japanese researchers have revealed for the first time that a specific protein plays a critical role in the development and metastasis of highly aggressive prostate and breast cancer cells. The study reports that large amounts of the fatty acid-binding protein 5 (FABP5), a kind of transport protein for fatty acids, promotes processes associated with cancer […]
Common skin cancer can signal increased risk of other cancers
People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study by researchers at the Stanford University School of Medicine. The increased susceptibility is likely caused […]
Discovery could lead to better treatment for leukemia
Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown. Scientists from the University of Illinois […]
New lung cell type discovered: A previously unknown airway cell type may be a key to efforts to cure cystic fibrosis
In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than […]