Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring about a particular trait or disease. “The challenge has been that many of these variants are difficult to interpret,” said Jesse […]
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Model maps out ‘arms race’ between cancer and immune system, predicts effectiveness of immunotherapy
Researchers have created a mathematical model that can determine the impact of the immune system on tumor evolution. The information gained from using this model may be able to be used to predict whether immunotherapy is likely to be effective for a patient’s cancer, helping to guide treatment decisions. Immune cells recognize tumors by detecting […]