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The innate immune system may be able to be trained to react to viral infections more efficiently by repeated exposure to anti-viral signaling molecules. Mammalian cells seem to be able to memorize anti-viral stimulation at the level of DNA-packaging molecules, enabling faster and greater activation of anti-viral genes in subsequent stimulations, according to a study […]
Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in such transplantation techniques and supportive care measures, has led to greater numbers of long-term HSCT survivors. Consequently, an increasing patient population is impacted by […]
Clinicians, scientists and public health professionals should proudly “declare victory” in their efforts to extend the human lifespan to its very limits, according to University of Illinois at Chicago epidemiologist S. Jay Olshansky. In an article published in the Journal of the American Medical Association, Olshansky writes that the focus should shift to compressing the […]
Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age. A study led by the University of Exeter Medical School has found that certain genes and pathways that regulate splicing factors — a group of proteins in […]
Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common cold to heart and asthma attacks. But progress in treating chronic illness, where the cause of the problem is often unknown — and, in fact, may no longer even be […]
Our immune system is working every day to protect us from bacteria, viruses, and parasites, but it can also detect when our own cells are damaged. Research led by Lancaster University has now discovered how skin cells alert the immune system, when their DNA is damaged in the absence of infection. This DNA damage can […]
The overall mortality in patients suffering non-neonatal tetanus is high. Efforts to reduce mortality in one sub-Saharan African intensive care unit (ICU) by implementing a standard tetanus protocol did little to change mortality rates, although they shifted causes of deaths, researchers have now reported in PLOS Neglected Tropical Diseases. Tetanus is a vaccine-preventable neglected disease […]
An opt-out organ donation register is unlikely to increase the number of donations, according to a new study from Queen Mary University of London. The researchers say donors should actively choose to be on the register by opting-in to ensure they genuinely want to donate their organs and to limit families from refusing the donation […]
Over-the-counter (OTC) drugs and dietary supplements are widely used and popular, with US households spending an average of almost USD 350 annually on OTC products. In 2006 an average of EUR 67.50 was spent per person on OTC products in Germany. The use of various OTC drugs and dietary supplements is highly prevalent in Europe […]
Sauna bathing is an activity used for the purposes of pleasure, wellness, and relaxation. Emerging evidence suggests that beyond its use for pleasure, sauna bathing may be linked to several health benefits. A new report published in Mayo Clinic Proceedings found that sauna bathing is associated with a reduction in the risk of vascular diseases, […]