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A growing number of infections — such as pneumonia, gonorrhea and tuberculosis — are becoming harder to treat, as bacteria evolve defenses against antibiotics faster than we can develop new drugs to replace them. Duke University game theorist David McAdams says faster, more accurate tests for drug-resistant infections are being developed that could, at least […]
A KAIST research team developed a microfluidic-based drug screening chip that identifies synergistic interactions between two antibiotics in eight hours. This chip can be a cell-based drug screening platform for exploring critical pharmacological patterns of antibiotic interactions, along with potential applications in screening other cell-type agents and guidance for clinical therapies. Antibiotic susceptibility testing, which […]
Pneumonia, a respiratory disease that kills about 50,000 people in the United States every year, can be caused by many different microbes, including bacteria and viruses. Rapid detection of pneumonia is critical for effective treatment, especially in hospital-acquired cases which are often more severe. However, current diagnostic approaches often take several days to return definitive […]
By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. But, in a new study, researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco, report finding tell-tale evidence of the condition’s infectious agent in the […]
As co-leaders of an international collaboration, scientists at Scripps Research have discovered that tethering four antibodies together may be an effective strategy for neutralizing all types of influenza virus known to infect humans. The research, published this week in Science, suggests this strategy could lead to influenza prevention tools with the strength and potency to […]
Seneca Valley Virus sounds like the last bug you’d want to catch, but it could be the next breakthrough cancer therapy. Now, scientists at the Okinawa Institute of Science and Technology (OIST) and the University of Otago have described exactly how the virus interacts with tumors — and why it leaves healthy tissues alone. The […]
A research group at KAIST presented a novel biosensor which can produce diverse, high-level microbial cell factories. The biosensor monitors the concentration of products and even intermediates when new strains are being developed. This strategy provides a new platform for manufacturing diverse natural products from renewable resources. The team succeeded in creating four natural products […]
A defective gene causes thick, sticky mucus to build up in the lungs of patients with cystic fibrosis (CF). There, it traps bacteria, causing patients to develop frequent lung infections that progressively damage these vital organs and impair patients’ ability to breathe. Most patients with this progressive genetic disorder die by the fourth decade of […]
In a potential game changer for the health care industry, a new cell phone app and lab kit now allow a smartphone to identify bacteria from patients anywhere in the world. With the new app, doctors will be able to diagnose diseases and prescribe the appropriate antibiotic within a one-hour office visit, meaning faster recovery […]
New research showing that the first bacteria introduced into the gut have a lasting impact may one day allow science to adjust microbiomes — the one-of-a-kind microbial communities that live in our gastrointestinal tracts — to help ward off serious chronic diseases. Findings by U of A microbial ecologist Jens Walter and his colleagues suggest […]