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THURSDAY, Sept. 13, 2018 — Lumoxiti injection has been approved to treat certain instances of relapsed or refractory “hairy cell” leukemia (HCL), the U.S. Food and Drug Administration said Thursday. Lumoxiti (moxetumomab pasudotox-tdfk) is among a novel class of drugs called CD22-directed cytotoxins to treat HCL, the agency said. It was approved for adults who […]
Scientists at The Wistar Institute have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics for infectious agents as well as for diverse implications in therapeutic delivery. This critical development was published online in the journal […]
Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis (MS), providing a better understanding of the individualized nature of the disease. MS has long been characterized as a disease of the brain’s white matter, where immune cells destroy myelin—the fatty protective covering on nerve cells. The destruction of myelin (called demyelination) was believed […]
A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, new research has found. A team led by researchers at The Ohio State University has developed and tested a vaccine that employs an uncommon two-pronged approach to fighting the virus, which is spread by mosquitos and is most serious for pregnant women […]
Researchers have identified a protein that powers the virulence of the bacteria that causes gonorrhea, opening the possibility of a new target for antibiotics and, even better, a vaccine. The findings, published today in PLOS Pathogens, are especially important since the microbe, Neisseria gonorrhoeae, is considered a “superbug” because of its resistance to all classes […]
A small-molecule drug is the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD). The study, which appears online in Cell, sheds light on […]