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A mechanism for how the disease amyotrophic lateral sclerosis, or ALS, evolves has been discovered at Umeå University, Sweden. The discovery concerns how proteins with a defect structure spread the deformation to other proteins, according to results in a new thesis. The discovery can open up for novel pharmaceutical developments in the future. “We’ve been […]
Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander […]
Researchers from Charité — Universitätsmedizin Berlin have studied motor and cognitive effects of deep brain stimulation in patients with Parkinson’s disease. Their results show that the adverse cognitive effects of deep brain stimulation are linked to a different neural pathway than that responsible for the treatment’s desired motor effects. This finding will help optimize treatments […]
Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson’s disease, according to new research from Rice University. “Inflammation and fatigue in early, untreated Parkinson’s disease” will appear in an upcoming edition of Acta Neurologica Scandinavica. It is one of the first studies to link […]
There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration. Researchers from the University of South Australia and the Third Military Medical University in China have discovered a signal pathway within cells, and also invented a potential drug that could stop degeneration […]
Parkinson’s disease was first described by a British doctor more than 200 years’ ago. The exact causes of this neurodegenerative disease are still unknown. In a study recently published in eLife, a team of researchers led by Prof. Henning Stahlberg from the Biozentrum of the University of Basel has now questioned the previous understanding of […]