Humans are creating or exacerbating the environmental conditions that could lead to further pandemics, new University of Sydney research finds. Modeling from the Sydney School of Veterinary Science suggests pressure on ecosystems, climate change and economic development are key factors associated with the diversification of pathogens (disease-causing agents, like viruses and bacteria). This has potential […]
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Apes mount a much stronger early immune response compared to African and Asian monkeys
A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions. The study was published on March 26 […]
Researchers present fragment-based computational design of antibodies that target structured epitopes
Antibodies are central to infection control and prolonged immunity. Key tools in biomedical research, antibodies are also used to diagnose human diseases and detect adaptive immunity to past infections with particular pathogens. While existing methods to discover and generate antibodies are successful, they also have important limitations, such as hard targets (short-lived, homologous, or unstable) […]