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In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing neuropathic pain—a difficult-to-treat, chronic pain associated with nerve trauma, chemotherapy and diabetes. A new study in Cell, led by Michael […]
African Americans who smoke cigarettes are more likely than those who don’t smoke to develop peripheral artery disease, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. Peripheral artery disease (PAD) is a narrowing of arteries other then those directly serving the […]
(HealthDay)—Appropriate use criteria have been developed for peripheral artery intervention (PAI) in peripheral artery disease, according to a report published online Dec. 17 in the Journal of the American College of Cardiology. Steven R. Bailey, M.D., from the University of Texas Health Science Center at San Antonio, and colleagues address appropriate use criteria in the […]
Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models of the disease. Mice, for instance, don’t show the same symptoms as humans, even when misfolded TTR accumulates in their organs. Now, scientists […]