In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King’s College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of […]
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Human Body-on-Chip platform enables in vitro prediction of drug behaviors in humans
Drug development is an extremely arduous and costly process, and failure rates in clinical trials that test new drugs for their safety and efficacy in humans remain very high. According to current estimates, only 13.8% of all tested drugs demonstrate ultimate clinical success and obtain approval by the Food and Drug Administration (FDA). There are […]
Diabetes prediction tool overestimates risk and creates unnecessary anxiety
The FINDRISC questionnaire has been used extensively to predict a person’s degree of risk for getting type 2 diabetes, but new findings show that it does not adequately identify the most vulnerable individuals. Type 2 diabetes is caused by lifestyle and genes. People who don’t exercise, or who are overweight or obese, are among those […]