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A new generation of miniature recording probes can track the same neurons inside tiny mouse brains over weeks—and even months. The new tools build on the success of the original Neuropixels probes released in 2017 and currently used in more than 400 labs. Neuropixels 2.0 are much smaller—about a third the size of their predecessors. […]
Approximately 98 percent of the human genome is made up of noncoding DNA, including enhancers, promoters, and other elements that regulate gene activity. The methods for studying these regions tend to be expensive, labor-intensive, and largely low-throughput. To really understand the functional geography of the noncoding genome, however, researchers need a way to isolate and […]