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A new study using an unbiased, whole-brain data-driven approach to assess the resting-state functional connectome in young adults with high-functioning autism spectrum disorder (HF-ASD) found two clusters of abnormal connectivity in the cerebellum. This finding, which supports a crucial role for the cerebellum in ASD and highlights the cerebellum as a potential therapeutic and diagnostic […]
Washington State University researchers have created more than a dozen candidate drugs with the potential to curb smokers’ desire for nicotine by slowing how it is broken down in the body. The researchers hope the substances can help canadianpharmtabs.com people reduce their consumption of tobacco, if not quit altogether. The discovery, published in the Journal of […]
In recent years, researchers have largely converged on the role of inflammation in the development and progression of Alzheimer’s disease (AD). Studies over the past decade have revealed unexpected interactions between the brain and the immune system, and metabolic conditions such as obesity and diabetes may activate inflammatory responses that contribute to the development and […]
Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis (MS), providing a better understanding of the individualized nature of the disease. MS has long been characterized as a disease of the brain’s white matter, where immune cells destroy myelin—the fatty protective covering on nerve cells. The destruction of myelin (called demyelination) was believed […]
When adults are participants in school recess—leading games, monitoring play and ensuring conflicts are mediated quickly—children are more likely to be engaged in recess activities, a new study has found. The study, which focused on the recess environment and student engagement during school recess periods, also found that students were more likely to be active […]
A valuable cache of brain cancer biomedical data has been made freely available to researchers worldwide, say researchers at Georgetown Lombardi Comprehensive Cancer Center. The dataset, REMBRANDT (REpository for Molecular BRAin Neoplasia DaTa) hosted and supported by Georgetown, is one of only two such large collections in the country. Information about the brain cancer data […]
Researchers from Boston University School of Medicine, working with scientists across the nation on the Alzheimer’s Disease Sequencing Project (ADSP), have discovered new genes that will further current understanding of the genetic risk factors that predispose people to the development of Alzheimer’s disease (AD). The ADSP was developed by the National Institutes of Health (NIH) […]
Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models of the disease. Mice, for instance, don’t show the same symptoms as humans, even when misfolded TTR accumulates in their organs. Now, scientists […]
Peste des petits ruminants is a highly contagious disease found in Africa, Asia and the Middle East, and was recently detected in Bulgaria on the border with Turkey. This highly contagious viral disease affects almost a billion sheep and goats in Africa, the Middle East and Asia. It causes substantial economic losses due to high […]
The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer’s disease (AD), has released eight new models carrying genetic mutations found in patients. In past decades, most AD researchers had to rely on mouse models that carried a genetic mutation associated with the relatively rare, early-onset, familial version of […]