A new review of data from 12 spaceflight experiments and simulated microgravity studies has shown that microgravity does not have a negative effect on stem-like cell-dependent tissue regeneration in newts, but in some tissues regeneration is faster and more robust. This valuable in vivo data has implications for understanding and managing the ability for repair […]
Squishing blood stem cells could facilitate harvest for transplants
Scientists at Winship Cancer Institute of Emory University, Children’s Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells’ stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants. Temporary squishiness could help drive blood-forming stem cells out of the bone marrow and into the blood, but the cells need to […]
Genetically encoded sensor isolates hidden leukemic stem cells
All stem cells can multiply, proliferate and differentiate. Because of these qualities, leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important area of cancer research. A team of Tel Aviv University researchers have now devised a novel biosensor that can isolate and […]
Could a stem cell jab help banish back pain for good?
Could a stem cell jab help banish back pain for good? A single jab of stem cells is being tested as a new treatment for lower back pain Doctors say the injection can help re-grow degenerated discs in the spine Researchers hope that trial in Ohio will cure cause of pain instead of symptoms A […]
Can stem cells help a diseased heart heal itself? Researchers achieve important milestone
A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves—a new model that would reduce the need for bypass surgery, heart transplants or artificial pumping devices. The study, recently published in Frontiers in Cell and Developmental Biology, involved removing connective […]
Engrafted stem cell-derived lung organoids that model human lung development
Researchers have now grown lung organoids from human embryonic stem cells (hESCs) that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs. The strategy is the first to generate both lung distal progenitor cells and mature AT1-like cells. The study is published in […]
Stem cell transplant cements Arizona men’s father-son bond
Thirty-five years after an Arizona man cared for his son when he was shot in their native Lebanon, the son is returning that devotion. Both the Rev. John Ibraham Sabbagh and his 54-year-old son, Ebby Sabbagh, are celebrating one year of going strong since the elder Sabbagh received a crucial stem cell transplant. After undergoing […]
Stem cells show promise as drug delivery tool for childhood brain cancer
The latest in a series of laboratory breakthroughs could lead to a more effective way to treat the most common brain cancer in children. Scientists from the University of North Carolina Lineberger Comprehensive Cancer Center, UNC Eshelman School of Pharmacy, and the UNC School of Medicine reported results from early studies that demonstrate how cancer-hunting […]