Stimulators of interferon genes (STING) are cytosolic sensors associated with the endoplasmic reticulum that respond to the presence of dsDNA in the cytosol, usually indicative of an invading pathogen or self-leaked DNA from damaging events. Image Credit: Christoph Burgstedt/Shutterstock.com Cytoplasmic DNA is firstly bound with the cyclic GMP-AMP synthase (cGAS) enzyme, which is activated to […]