(HealthDay)—Dr. Brad Cotton enjoyed working on the front lines as an emergency room doctor. Yet in March, as the coronavirus pandemic burst through the doors at hospitals across the world, Cotton left that more dangerous work behind. “I left emergency medicine because that was much higher risk. I’m actually still working full time for urgent […]
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Researchers isolate switch that kills inactive HIV
Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned off or deleted, eliminates dormant HIV reservoirs. “This is one of the key switches that the HIV field has been searching for three decades to find,” said Tariq […]
Scientists catch heartbeat ‘molecular switch’ in action
Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat. In a paper published in the journal Circulation Research, they used this technique to uncover the effects of genetic errors that contribute to […]
Faulty molecular master switch may contribute to AMD
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have found that interrupting TGF-beta signals to immune cells called microglia causes the cells to enter an activated, inflammatory state. […]