Last December, dancer Kathlenne “Kat” B. and her boyfriend Connor M., a musician, moved to New York City from Orange County, New York to grow their careers. As part of that new chapter in their lives, they also wanted to adopt a dog. Once the couple rented an apartment on Manhattan’s Upper East Side, they […]
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Team cracks century-old mystery over the health struggles of explorer Ernest Shackleton
Researchers from Massachusetts General Hospital (MGH) appear to have solved the 120-year-old mystery surrounding the failing health of famed Antarctic explorer Sir Ernest Shackleton over the course of his daring expeditions to Antarctica in the early part of the twentieth century. In a paper published online in the Journal of Medical Biography, the team moved […]
Research team reports new class of antibiotics active against a wide range of bacteria
Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature. The World Health Organization (WHO) has declared AMR as one of the top 10 global public […]
International team identifies a new regulatory pathway in bladder cancer
Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled “GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma” in Science Signaling. The KEAP1-NRF2 pathway plays a key role in cancer prevention and protective cellular responses to oxidative and electrophilic stress. In normal and premalignant tissues […]
Hope Solo Pregnant With Twins After Miscarriage: 'Miniature Soccer Team'
Congratulations times two! Hope Solo is pregnant with twins after suffering a previous pregnancy loss. “My husband and I get to practice equality from the very beginning with one boy and one girl,” the professional soccer player, 38, revealed on a Tuesday, December 17, BeIN Sports appearance. “Miniature soccer team on the way.” Solo’s baby […]
Team plucks needle from genomic haystack, finding essential transcription factor binding sites
Using CRISPR/Cas9 knockout screens a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer cells, plucking useful needles from a massive genomic haystack that contains millions of transcription factor binding sites. They found that essential FOXA1 binding sites act […]
Research team develops new genetic-based epilepsy risk scores
An international team of researchers led by Cleveland Clinic has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment. This analysis is the largest study of epilepsy genetics to date, as well as the largest study of epilepsy using human samples. Published in […]
This Video of 6-Year-Old Girl Outrunning an All-Boy Football Team Is Everything
A few years ago, a hashtag popped up that people either loved or hated: #LikeAGirl. The campaign, launched by Always, was meant as a way to reclaim a popular insult young women hear (you know, “you run like a girl!” to somehow mean slow or uncoordinated?! We think it’s bullshit, too). Many embraced it — […]
Team isolates antibodies that neutralize GI bug norovirus
Researchers at Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of acute gastrointestinal illness in the world. These antibodies, described this week in the journal Gastroenterology, “have high potential” for improving diagnosis and treatment of norovirus illness as well as furthering efforts to develop the […]
Research team develops predictor for immunotherapy response in melanoma
In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy. The predictor was developed by Noam Auslander, Ph.D., with other researchers in the Center for Cancer Research (CCR) at the National […]