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Medical advances have dramatically increased the life expectancy of patients with sickle cell disease, but as patients are living longer, they are increasingly experiencing organ damage leading to early death. Now, researchers at the University of Pittsburgh and UPMC, supported by a $19.2 million National Institutes of Health grant, will lead the largest clinical trial […]
Fitness fanatic, 21, has a ‘mechanical heart’ fitted after the failure of his organ ‘became too severe to wait for a life-saving transplant’ Greg Marshall developed a ‘chest infection’ and ‘asthma’ at the end of 2016 Diagnosed with heart failure after he suddenly collapsed in a car park Pacemaker failed, forcing Mr Marshall to have […]
If there’s one aspect of parenthood Prince Harry already has down pat, it’s the dad jokes! The former military pilot started practicing his humor ahead of the birth of his first child, son Archie, with Duchess Meghan. Harry and Meghan — who tied the knot at St George’s Chapel at Windsor Castle in May 2018 […]
The heart of the clock, device, medications can help to obtain rate and rhythm. In addition, a non-drug Alternative is gaining in importance, the so-called catheter ablation, is reported by Priv.-Doz. Dr. René Andrié from the heart center, Helios Klinikum Siegburg, Germany, on a training event for pharmacists in Schladming, Austria. More or less happens […]
Patients diagnosed with pancreatic cancer face a poor prognosis because the tumor forms dense scar-like tissue that is difficult for chemotherapy drugs to penetrate, but a new model may help researchers develop new therapies. “More than 85 percent of pancreatic tumors form this fibrous tissue,” explained Assistant Professor Joshua Reineke of the South Dakota State […]
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gene expression and enhanced anti-cancer immunity. It is the first time this particular kinase has been linked to gene silencing in mammals. Jean-Pierre Issa, MD, Director of the Fels Institute […]
Parents beg officials to approve the life-saving £450,000 drug which can treat the rare condition crippling their five-year-old son Finley Newell, from Haddenham, Buckinghamshire, has spinal muscular atrophy A drug already exists which could improve his life but the NHS can’t buy it In August regulators said the £450,000 drug was not value for money […]
‘Just as everyone’s spots were clearing up, mine became worse’: Woman, 28, who had perfect skin throughout her teenage years is left with a permanently scarred face after developing severe acne in her TWENTIES Emilie Love first developed minor breaks outs when she was 16 years old Years later, her blemishes turned into cystic acne […]
Pin Look, we know sugar — especially the refined sugar in candy — isn’t good for us. And sure, we try to avoid it whenever possible… but what about Halloween? Is it really that bad to let kids indulge like this once a year? To answer this question, we turned to the professionals who deal […]
Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss. Therapies targeting a specific cytokine, vascular endothelial growth factor (VEGF), have transformed clinical care; however, not all patients respond well. A new report in […]