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A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-cell ALL), even when the drug doesn’t meet the FDA’s strict manufacturing standards. The findings, published in Blood, may help widen […]
Now you’re safe to take a treatment holiday from a life-saving kidney cancer pill which causes terrible side effects More than 15,000 Britons are taking daily pills to treat advanced kidney cancer The highly effective medication causes progressively worse side effects A study has shown a treatment holiday has no impact on life expectancy Patients with […]
Approximately 50 million people worldwide live with Alzheimer’s or other related forms of dementia. Alzheimer’s disease leads to memory loss and impairment in cognitive function, and is the most common cause of dementia among older adults. While certain treatments can help reduce symptoms and sometimes reduce disease progression, there is currently no way to prevent […]
It is not necessary to tailor the medication doses to patients, at thestart of treatment, for patients to have a good effect. This is shown by a new Norwegian study led by Professor Espen A. Haavardsholm. Ulcerative colitis, Chrohn’s disease, rheumatoid arthritis, psoriatic arthritis, spondylitis and psoriasis are chronic inflammatory diseases of the intestines, joints […]
Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer. A Chinese research team has now developed a novel form of photodynamic tumor therapy for the treatment of deep tumors that works without external irradiation. The light source is built into the drug and […]
In an observational study, Mayo Clinic researchers report that the combination of casirivimab and imdevimab—two monoclonal antibody treatments under Food and Drug Administration emergency use authorization—keep high-risk patients out of the hospital when infected with mild to moderate COVID-19. The findings appear in The Lancet’s EClinicalMedicine. Nearly 1,400 Mayo Clinic patients were enrolled in the […]
A team of researchers at Texas A&M University, Northwestern University, and ImmunoGenesis has discovered a treatment for glioblastoma that has promising implications for the human version of the aggressive cancer form that grows in the brain. Published today in Clinical Cancer Research, a journal of the American Association for Cancer Research, the study describes the […]
A large, detailed look at patients taking HIV-prevention drug therapy finds strong adherence soon after patients get the prescription, but less consistent use thereafter, particularly among groups considered high priority for receiving the medication. The study, published August 26 in JAMA Network Open, examined data from 13,906 members of Kaiser Permanente in Northern California referred […]
A new UCL and UCLH-led study of patients with cerebral venous thrombosis (CVT) following COVID-19 vaccination, provides a clearer guide for clinicians trying to diagnose and treat patients. The research, published in The Lancet, is the most detailed account of the characteristics of CVT, when it is caused by the novel condition vaccine-induced immune thrombotic […]
COVID-19 is marked by heightened inflammation and abnormal clotting in the blood vessels, particularly in the lungs, and is believed to contribute to progression to severe disease and death. New trial results show that administering a full dose of a standard blood thinner early to moderately ill hospitalized patients with COVID-19 could halt the thrombo-inflammation […]