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Research has found fidaxomicin, an antibiotic usually used to treat bowel infections, prevents growth of resistant strains of Mycobacterium tuberculosis (MTb) in the lab. Published in the Journal of Medical Microbiology, the research found that fidaxomicin was more effective than existing tuberculosis (TB) medication at preventing growth of the bacterium that causes TB. Researchers compared […]
Scientists from Trinity have discovered both how TB puts the brakes on our immune engines and how we can kick-start those engines back into gear—providing hope that improved treatment options could soon be on the horizon. Although ancient, TB is still the world’s deadliest infectious disease. While it is rampant in Africa, the growing problem […]
Semiconducting polymers, very large chain-like molecules made from repeating sub-units, are increasingly drawing the attention of researchers because of their potential applications in organic electronic devices. Like most semiconducting materials, semiconducting polymers can be classified as p-type or n-type according to their conducting properties. Although p-type semiconducting polymers have seen dramatic improvements thanks to recent […]
Caline Mattar, MD, an assistant professor of medicine in the Division of Infectious Diseases at Washington University School of Medicine in St. Louis, has been appointed a chair of the Expert Advisory Group for the Global Antimicrobial Resistance Research and Development Hub. Based in Germany, the organization formed in May 2018 to pool international resources […]
A new study conducted by researchers in Leicester and Nottingham has shown the potential for a new blood test to not only diagnose human tuberculosis (TB) but also identify those at most risk of developing the disease, according to findings published in medical journal Clinical Infectious Diseases. Despite recent reductions, England still has one of […]
A growing number of infections — such as pneumonia, gonorrhea and tuberculosis — are becoming harder to treat, as bacteria evolve defenses against antibiotics faster than we can develop new drugs to replace them. Duke University game theorist David McAdams says faster, more accurate tests for drug-resistant infections are being developed that could, at least […]
A world free of tuberculosis (TB) is possible by 2045 if increased political will and financial resources are directed towards priority areas including providing evidence-based interventions to everyone, especially to high risk groups, and increasing research to develop new ways to diagnose, treat, and prevent TB. Funding this response will require substantial investments, and accountability […]
A new experimental antibiotic for tuberculosis has been shown to be more effective against TB than isoniazid, a decades-old drug which is currently one of the standard treatments. In mouse studies, the new drug showed a much lower tendency to develop resistance, and it remains in the tissues where the Mycobacterium tuberculosis bacteria reside for […]
By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Yale researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them. Biofilms form when bacterial cells gather and […]
Tuberculosis (TB) is the leading infectious cause of death worldwide, killing roughly 1.6 million people in 2017. In the past 200 years, TB claimed the lives of more than one billion people — more deaths than from malaria, influenza, smallpox, HIV/AIDS, cholera and plague combined. Recently, the global health community has strengthened its efforts and […]