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Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences. Mojgan Naghavi, Ph.D., professor of Microbiology-Immunology and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, was senior author of the study. […]
Researchers have mapped out some of the mechanisms that may affect women’s fertility from the teenage years to menopause. These mechanisms largely depend on naturally occurring chromosome errors—errors that vary depending on age group. This is the conclusion by an international research group in a new study, led by researchers from the University of Copenhagen. […]
Researchers at Oregon State University have made an important advance toward understanding why certain cells in the nervous system are prone to breaking down and dying, which is what happens in patients with ALS and other neurodegenerative disorders. The study into the role a protein known as heat shock protein 90 plays in intracellular signaling […]
A research team at the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has discovered the potentials of a SECISBP2 protein in adipose tissue macrophages (ATMs) as a therapeutic biomarker in the treatment of chronic diseases such as type 2 diabetes, hyperlipidemia, cardiovascular diseases and cancers caused by obesity-induced insulin resistance. The findings, […]
Current anti-cancer drugs can be quite effective but too often, tumors are not fought off completely and end up returning. A recent study published in The FASEB Journal provides the first evidence that some cancer cells evade therapy by switching over to alternative molecular mechanisms that are not affected by existing anti-cancer treatments. A research […]
Researchers at CNRS, Université Côte d’Azur and Inserm have demonstrated a new mechanism related to the onset of migraine. They found how a mutation that causes dysfunction in a protein which inhibits neuronal electrical activity induces migraines. These results, published in Neuron on December 17, 2018, open a new path for the development of anti-migraine […]
Insulin is secreted from the beta cells located in the pancreas, and the hormone is crucial for the maintenance of normal blood sugar levels. Deficiency of insulin leads to diabetes, characterized by elevated blood sugar. Diabetes most commonly presents in childhood as type 1 diabetes and in adults as type 2 diabetes. Sometimes diabetes is […]
Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer’s disease. Alzheimer’s disease is associated with two neuropathologies: amyloid plaques and tau aggregates, or tau protein accumulated in […]