Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective. Importantly, the data also reveals how anti-obesity drugs like Ozempic, actually work, which to date has been a mystery. In early November the FLOW trial of the drug […]

Many people from racial and ethnic minority groups brace themselves for insults and judgments before medical appointments, according to a new survey of patients that reaffirms the prevalence of racial discrimination in the U.S. health system. The KFF survey of nearly 6,300 patients who have had care in the past three years found that about […]

Spinal muscular atrophy (SMA) is a devastating pediatric neuromuscular disorder caused by loss-of-function mutations in the SMN1 gene, which prevents the body from producing enough of the survival motor neuron (SMN) protein that is important for development and neuronal function. Motor neurons affected by SMA include those that control movement in the arms, legs, face, […]

A new Peter Mac study using a pioneering drug has successfully controlled the growth of tumors and overcome existing drug resistance in multiple cancer types. An enzyme critically associated with tumor growth, called cyclin-dependent kinase 2 (CDK2), has long been a target for researchers but it has been incredibly difficult to create a therapeutic drug […]

A recent study demonstrated the safety of cilostazol in patients with mild cognitive impairment (MCI), but did not demonstrate any efficacy in preventing disease progression. However, after administration of cilostazol, the blood concentrations of the albumin and β-amyloid complex (albumin-Aβ complex) increased in the treated patients compared with those receiving placebo. This finding indicates that […]

Source: Read Full Article

A new study highlights how stigmatizing attitudes about individuals with acne may influence social and professional perceptions. Led by investigators from Brigham and Women’s Hospital, the study found that individuals with acne face stigmatizing attitudes from the general public in professional and social scenarios. The researchers also found that more severe acne and darker skin […]

Reviewed The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of long-term, brain-related disease, according to a new study. Researchers from the University of Virginia School of Medicine and Naval Medical Research Command (NMRC) led the study, which […]

Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham health care system, have found that statins, the most prescribed class of drugs to treat high cholesterol, reduced the risk of heart attack and stroke among two groups at high risk for heart disease: older adults with chronic kidney disease and […]

Reviewed New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood. Thinning of the orbitofrontal cortex, a region in the brain that affects emotion, during adolescence was also associated with increased depressive symptoms later in life. […]