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More than three decades of research on Alzheimer’s disease have not produced any major treatment advances for those with the disorder, according to a UCLA expert who has studied the biochemistry of the brain and Alzheimer’s for nearly 30 years. “Nothing has worked,” said Steven Clarke, a distinguished professor of chemistry and biochemistry. “We’re ready […]
Long-term nursing home residents with hypertension do not experience significant benefits from more intensive antihypertensive treatment, according to a study published online July 22 in the Journal of the American Geriatrics Society. Kenneth S. Boockvar, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues examined the number of […]
Cutting off and then restoring blood supply to a limb following a stroke reduces tissue damage and swelling and improves functional recovery, according to a new study in mice published in JNeurosci. The simple, noninvasive technique could be developed into a treatment for stroke patients of varying severity. Remote ischemic limb conditioning utilizes a blood […]
Eating disorder researchers at The University of Texas Health Science Center at Houston (UTHealth) have discovered a neurocircuit in mice that, when activated, increased their stress levels while decreasing their desire to eat. Findings appear in Nature Communications. The scientists believe their research could aid efforts to develop treatments for a serious eating disorder called […]
A research team at the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has discovered the potentials of a SECISBP2 protein in adipose tissue macrophages (ATMs) as a therapeutic biomarker in the treatment of chronic diseases such as type 2 diabetes, hyperlipidemia, cardiovascular diseases and cancers caused by obesity-induced insulin resistance. The findings, […]
Spouses in older marriages are increasingly taking on the role of their partner’s caregiver in dealing with chronic conditions like heart disease, memory loss, and cancer. In a growing number of instances, both spouses care for each other as they struggle with any one of a variety of health issues such as arthritis, diabetes, and […]
Alzheimer’s Research UK is calling on the Prime Minister to back worldwide commitments to invest in more dementia research as new data out today shows deaths due to the condition continue to rise. According to the Office of National Statistics, Alzheimer’s disease and other dementias remain the leading cause of death in England and Wales […]
A beautiful landscape painting, a beautiful piano sonata—art and music are almost exclusively described in terms of aesthetics, but what about math? Beyond useful or brilliant, can an abstract idea be considered beautiful? Yes, actually—and not just by mathematicians, reports a new study in Cognition. Coauthored by a Yale mathematician and a University of Bath […]
For decades, biomedical researchers have used mouse behavior to study pain, but some researchers have questioned the accuracy of the interpretations of how mice experience pain. Now, Rutgers University-Camden neuroscientist Nathan Fried and colleagues from the University of Pennsylvania have developed a method that can more accurately gauge pain in mice, which could lead researchers […]
Distinct markers in the blood of people with coeliac disease have been detected within a few hours of gluten being consumed. The findings address a longstanding mystery about what drives the adverse reaction to gluten in coeliac disease and could lead to a world-first blood test for diagnosing the disease. A potential blood-based test would […]