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A combination of the kinase-inhibitor drug cabozantinib and the immunotherapy drug nivolumab can make curative surgery possible in some liver cancer patients who would normally not be considered surgery candidates. Results published July 29 in the journal Nature Cancer by researchers at the Johns Hopkins Kimmel Cancer Center describe the benefits of this drug combination. […]
Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma in patients with metastatic disease. Researchers from Dana-Farber Cancer Institute report a response rate of 24 percent across all risk categories of patients given an oral first-in-class agent that targets hypoxia inducible factor (HIF) 2-a, […]
An investigational cancer drug that targets tumors caused by mutations in the KRAS gene will be evaluated in phase 2 clinical trials, following promising safety and efficacy results in preliminary human studies and excellent results in animal studies. The drug, developed by Amgen and currently referred to as AMG 510, is the first therapy to […]
Hope for thousands of prostate cancer sufferers as trial finds a ‘precision’ drug can help incurable patients live almost four months longer Lynparza extended survival of men with advanced prostate cancer by 7.4 months That is more than double the NHS hormonal treatments (3.5 months) Lynparza works by targeting faulty DNA which helps cancer cells […]
Stephen Fry, 62, posted a video on his Twitter timeline last year revealing he had been diagnosed with prostate cancer. Prostate cancer is the most common cancer in men in the UK. In the video the TV star revealed that a routine-check up spotted an early warning sign of prostate cancer. Referring to his doctor, […]
Medical advances have dramatically increased the life expectancy of patients with sickle cell disease, but as patients are living longer, they are increasingly experiencing organ damage leading to early death. Now, researchers at the University of Pittsburgh and UPMC, supported by a $19.2 million National Institutes of Health grant, will lead the largest clinical trial […]
A recent study conducted jointly by the Tissue Engineering Research Group of the Department of Histology and the family medicine Unit of the University of Granada (UGR) has highlighted the conceptual, attitudinal and procedural profile of resident hospital doctors specialising in family medicine in relation to advanced therapies. According to the European Medicines Agency, cell […]
Investigators at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) have used magnetoencephalography (MEG) – a technology that measures brain activity by detecting the weak magnetic fields produced by the brain’s normal electrical currents—to measure levels of the iron-based mineral called magnetite in the human brain. While magnetite is known to be […]
Epigenetic therapy with histone deacetylase (HDAC) inhibitors is worth pursuing in hormone receptor positive advanced breast cancer, suggests a phase III trial reported today at the ESMO 2018 Congress in Munich. Endocrine therapies are the foundation of treatment for patients with hormone receptor positive breast cancer. However, resistance to endocrine therapy is common, leading to […]
A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer. The research showed that using the immunotherapy drug pembrolizumab and the experimental agent SD-101, a sequence of nucleic acids that mimics […]